ObjectiveTo analyse patterns of concomitant allergic reac

\n\nObjective\n\nTo analyse patterns of concomitant allergic reactions to the five epoxy (meth)acrylates in relation to exposure.\n\nMethods\n\nWe reviewed the

1994-2008 patch test files at the Finnish Institute of Occupational Health (FIOH) for reactions to the five epoxy (meth)acrylates, and examined the patients’ medical records for exposure.\n\nResults\n\nTwenty-four patients had an allergic reaction to at least one of the studied epoxy (meth)acrylates, but specific exposure was found only in five patients: two bis-GMA allergies from dental products, two bis-GA allergies from UV-curable printing inks, and one bis-GA allergy from an anaerobic glue. Only 25% of the patients were negative to DGEBA epoxy resin.\n\nConclusions\n\nThe great

majority of allergic patch test reactions ATM/ATR inhibitor to bis-GMA, bis-GA, GMA and bis-EMA were not associated with specific exposure, and cross-allergy to DGEBA epoxy resin remained a probable explanation. However, independent reactions to bis-GA indicated specific exposure. Anaerobic sealants may induce sensitization not only to aliphatic (meth)acrylates but also to aromatic bis-GA.”
“PURPOSE: To click here compare refractive state changes in eyes implanted with toric intraocular lenses (IOLs) vs non-toric IOLs, after cataract extraction. DESIGN: Retrospective, comparative. METHODS: In a single institution, 121 eyes underwent phacoemulsification and implantation with either nontoric IOLs or.toric IOLs. The spherical value, cylindrical value, spherical equivalent (SE) of refractive error, and visual acuity were measured preoperatively and 1, 3, and 6 months after surgery. Main outcome measures were the pattern of changes of spherical, cylindrical, and SE values based on postoperative time, between different IOL types. RESULTS: The groups, which included patients who underwent surgery with SN6OWF (Group I), SA6AT3 (Group 11-3), SA6AT4 (Group II-4), and

SA6AT5 lenses (Group 11-5), contained 37, 29, 23, and 32 eyes, respectively. The cylindrical value was significantly Daporinad Metabolism inhibitor decreased in all groups (P smaller than .05). Before surgery, the SE of refractive errors was estimated as -0.21, -0.10, -0.20, and -0.22 in the respective groups. The actual remaining SE values were -0.19, -0.24, -0.42, and -0.56 at 1 month; -0.17, -0.26, -0.57, and -0.64 at 3 months; and -0.17, -0.26, -0.70, and -0.74 at 6 months postoperatively, respectively. The follow-up SE values in groups land 11-3 were similar (P bigger than .05 in both groups); however, significant myopic changes were observed in Groups 11-4 and II-5 after surgery, vs Group I (P smaller than .05).

In Brazil, the Ministry of Health estimates that 15%

of t

In Brazil, the Ministry of Health estimates that 15%

of the population has had contact with HBV, and that the mean rate of chronic carriers in Northeastern Brazil is around 0.5%. Objective: The aim of this study was to assess the prevalence of HBV markers in pregnant women receiving prenatal care at the public maternity hospitals Selleck GW4869 of Sao Luis.\n\nMethods: Demographical and epidemiological data were collected from 541 pregnant women according to the research protocol. Blood samples were collected, and the anti-HBc test was performed first. If positive, the sample was subsequently tested for HBsAg and anti-HBs. All HBsAg and/or anti-HBc positive samples were additionally tested for HBV-DNA.\n\nResults: 40 (7.4%) pregnant women turned out positive for anti-HBc. Of those, five (0.9%) were HBsAg positive, four (0.7%) were anti-HBc positive with negative HBsAg and anti-HBs, and 31 (5.7%) were positive for anti-HBc DMXAA in vitro and anti-HBs. Anti-HBc

positivity was associated with family history of hepatitis and education level below 11 years of schooling. HBV-DNA was positive in only one HBsAg-positive sample. There was no HBV-DNA positivity among HBsAg negative samples.\n\nConclusions: The prevalence of HBsAg in pregnant women in this study confirmed that Sao Luis is a low endemicity area. Occult hepatitis B was not detected in these samples. (C) 2012 Elsevier Editora Ltda. All rights reserved.”
“The use of Pseudomonas stutzeri lipase (PSL) as a biocatalyst for aminolysis reactions with bulky substrates has been investigated. PSL compared favorably to Novozym(R) 435 ( immobilized

Candida antarctica lipase B, NOV435) in the aminolysis of various bulky methyl esters and amines. While NOV435 demonstrated a higher rate of aminolysis with methyl 2-phenylpropionic acid as the acyl donor, PSL outperformed NOV435 with secondary amines as the nucleophile. Methanol inhibition and a low affinity for bulky acyl donors were found to be the two main reasons for relatively low rates in the PSL-catalyzed aminolysis reactions. It was demonstrated that the use of molsieve 4A had a significant effect on FDA-approved Drug Library mw the aminolysis rate and amide yield, since it enabled the effective removal of the inhibiting methanol from the reaction mixture.”
“Maintaining population diversity throughout generations of Genetic Algorithms (GAs) is key to avoid premature convergence. Redundant solutions is one cause for the decreasing population diversity. To prevent the negative effect of redundant solutions, we propose a framework that is based on the multi-parents crossover (MPX) operator embedded in GAs. Because MPX generates diversified chromosomes with good solution quality, when a pair of redundant solutions is found, we would generate a new offspring by using the MPX to replace the redundant chromosome.

At room temperature, the electromechanical parameters for PT and

At room temperature, the electromechanical parameters for PT and BT were found to decrease with increasing one-dimensional compression, except for the dielectric susceptibility epsilon(22) and piezoelectric coefficient e(24) of tetragonal BT. The variations of dielectric and piezoelectric parameters were analyzed according to the elastic Gibbs free-energy. (C) 2012 American Institute of Physics. [http://0-dx.doi.org.brum.beds.ac.uk/10.1063/1.4768903]“
“Study Design. A case report.\n\nObjective. To report the successful consecutive find more spinal osteotomies of multiple segments performed on a patient

with extremely severe kyphotic deformity.\n\nSummary of Background Data. There have been no reports on the experience and surgical strategy of spinal osteotomy on multiple segments for severe global spine deformity.\n\nMethods.

S63845 order A 48-year-old man, a patient with ankylosing spondylitis with “chin-on-pubis” deformity, underwent consecutive spinal osteotomies to correct the severe, fixed global kyphosis. The axial skeletons from the skull, all vertebrae, and both sacroiliac joints and hip joint were fused into a single bone. After both hip resectional arthroplasties for the first step, staged, sequential spinal osteotomies, including pedicle subtraction osteotomy (PSO) on C6, posterior vertebral column resection on T11-T12, and PSO on L3, were performed. Finally, both total hip arthoroplasties were performed.\n\nResults. selleck compound The chin-brow vertical angle improved from 140 degrees to 15 degrees. Correction angles of 45 degrees, 70 degrees, and 30 degrees in the cervical, thoracic, and lumbar spines, respectively, were achieved without complication. At the last follow-up, excellent improvement in activities of daily living and horizontal gaze were achieved.\n\nConclusion. This is the first report on C6 PSO and spinal osteotomies in whole spine segments. For patients with a severe global kyphotic deformity, it is important to place the patient in a stable prone position so that corrective surgery can be performed on the thoracolumbar spine. To accomplish this, initially correcting

the deformities in the hip joints and the cervical spine can yield excellent clinical results.”
“. The chemokine monokine induced by interferon-? (Mig) is involved in the recruitment of inflammatory cells and liver injury during hepatitis B virus (HBV) infection. HBV protein X contributes to Mig expression in vitro by activation of nuclear factor (NF)-?B; however, the molecular mechanisms by which HBV induces Mig expression in vivo are unknown. In this paper, we established a mouse model for HBV study by tail vein injection of HBV genome-containing adenovirus vectors. Host immune response to the secreted hepatitis B surface antigen and e antigen was detected and serum alanine aminotransferase (ALT) was elevated at different time points. We also demonstrated that peripheral and intrahepatic Mig expression was increased after Ad-HBV infection.

The data suggested that C1q-like might play an antiapoptotic and

The data suggested that C1q-like might play an antiapoptotic and protective role in inhibiting p53-dependent and caspase

3/9-mediated apoptosis during embryogenesis, especially in the brain development, and C1q-like should be a novel regulator of cell survival during zebrafish embryogenesis. (c) 2008 Elsevier Inc. All rights reserved.”
“The Bcl-2-associated athanogene, BAG, protein family through their BAG domain associates with the hear shock protein 70 (HSP-70) and modulates its chaperone activity. One member of this family, BAG3, appears to play an important role in protein homeostasis, as its expression promotes cell survival. Expression of BAG3 is enhanced by a variety of stress-inducing agents. Here we describe a role for BAG3 to modulate transcription or its own promoter through a positive feedback loop involving its 5′-UTR Cyclopamine molecular weight Sequence. Activation of the BAG3 promoter is mediated by the BAG domain and is independent of BAG3 association with the UTR sequence. Autoactivation of the BAG3 gene is observed in several cultures of human glial cells including gliomas, but not in several other non-glial cell lines such as He La and others. Results front cell fractionation and immunocytochemistry showed BAG3

in the cytoplasm as well as the nuclei of glial cells. These observations suggest that BAG3 gene expression is controlled by its own product and that this may be critical for the biological activity of BAG3 in some cell types. J. Cell. Biochem. 108: 1117- 1124, 2009. (C) 2009 Wiley-Liss, Inc.”
“Few cases of the

Citarinostat research buy pandemic influenza A H1N1 have been reported in very low birth weight infants. We report here a small outbreak in our NICU of 3 cases of influenza A/H1N1/09-10 in very low birth weight infants during the 2009-2010 H1N1 pandemic and describe their clinical presentations and favorable outcomes despite the lack of treatment. Pediatrics 2011;128:e1297-e1301″
“The major complication occurring with biliary stents is stent occlusion, frequently seen because of buy Prexasertib tumour in-growth, epithelial hyperplasia, and sludge deposits, resulting in recurrent jaundice and cholangitis. We report a prospective study with the results of first in man percutaneous intraductal radiofrequency (RF) ablation to clear the blocked metal stents in patients with malignant biliary obstruction using a novel bipolar RF catheter.\n\nNine patients with malignant biliary obstruction and blocked metal stents were included. These patients underwent intraductal biliary RF ablation through the blocked metal stent following external biliary decompression with an internal-external biliary drainage.\n\nAll nine patients had their stent patency restored successfully without the use of secondary stents. Following this intervention, there was no 30-day mortality, haemorrhage, bile duct perforation, bile leak, or pancreatitis.

More than one-third of practitioners had obtained qualifications

More than one-third of practitioners had obtained qualifications overseas and almost half of these practitioners provided no evidence of past study in professional issues and medical ethics.\n\nConclusions. Ageing, diversity in qualifications and training, English proficiency, and level of study in professional issues and medical ethics represent major challenges for the implementation of CM national registration in 2012.”
“Divergent selection

BIBF 1120 chemical structure between contrasting habitats can sometimes drive adaptive divergence and the evolution of reproductive isolation in the face of initially high gene flow. “Progress” along this ecological speciation pathway can range from minimal divergence to full speciation. We examine this variation for threespine stickleback fish that evolved independently across eight lake-stream habitat transitions. By quantifying stickleback diets, we show that lake-stream transitions usually coincide with limnetic-benthic ecotones. By measuring genetically based phenotypes, we show that these ecotones often generate adaptive divergence in foraging morphology. By analyzing neutral genetic markers (microsatellites), we show that adaptive divergence is often associated with the presence

of two populations maintaining at least partial reproductive isolation in parapatry. Coalescent-based simulations further suggest that these populations have diverged with gene flow within a few thousand generations, although we cannot rule out the https://www.selleckchem.com/products/blebbistatin.html possibility of phases of allopatric divergence. Finally, we find striking variation among the eight lake-stream transitions in progress toward ecological speciation. This variation allows us to hypothesize that progress

is generally promoted by strong divergent selection and limited dispersal across the habitat transitions. Our study thus makes a case for ecological speciation in a parapatric context, while also highlighting variation in the outcome.”
“Purpose. To evaluate BMS-754807 the diagnostic performance of ARFI imaging in differentiating between benign and malignant thyroid nodules smaller than 1 cm. Materials and Methods. 173 pathologically proven thyroid nodules (77 benign, 96 malignant) in 157 patients were included in this study. Receiver-operating characteristic curve (ROC) analyses were performed to assess the diagnostic performance of conventional ultrasound (US) and ARFI imaging in papillary thyroid microcarcinoma (PTMC). The independent risk factors for predicting PTMC were evaluated. Results. The mean SWV value of benign and malignant thyroid nodules were 2.57 +/- 0.79 m/s (range: 0.90-4.92 m/s) and 3.88 +/- 2.24 m/s (range: 1.49-9.00m/s) (P = 0.000). Az for VTI elastography score was higher than that for hypoechoic, absence of halo sign, and type III vascularity (P smaller than 0.05). The optimal cut-offs for VTI elastography score and SWV were score 4 and 3.10 m/s. Gender, hypoechoic, taller than wide, VTI elastography score bigger than 4, and SWV bigger than 3.

0001) Fourteen authors published the majority (70/124) of positi

0001). Fourteen authors published the majority (70/124) of positive reviews, and ten of these 14 had or have since developed a pCOI with various manufacturers of HES.\n\nLow-quality HES reviews reached different conclusions than high-quality meta-analyses from independent entities,

such as Cochrane Reviews. The majority of these find more low-quality positive HES reviews were written by a small group of authors, most of whom had or have since established ties to industry. The proliferation of positive HES reviews has been associated with increased utilization of an expensive therapy despite the lack of evidence for meaningful clinical benefit and increased risks. Clinicians need to be more informed that marketing efforts are potentially MEK inhibitor influencing scientific literature.”
“Objective. To assess the pathologic characteristics and prognostic significance of periprostatic lymph node (LN) metastasis of prostate cancer. The latter was performed by comparing biochemical recurrence (BCR)-free survival in cases of periprostatic LN metastasis versus matched patients showing pelvic LN metastasis. Methods and Materials. We identified 15 patients who underwent radical prostatectomy in our institution (1984-2011) showing positive periprostatic and negative pelvic LN with available follow-up information (group 1). These patients were matched 1:2 to patients with positive pelvic LN (group 2) for pertinent clinicopathologic parameters.

Results. Main locations of positive periprostatic LN were posterior base and mid posterolateral. Overall higher rate of positive margins,

smaller LN, and metastasis size were encountered in group 1 compared with group 2. At 5 years postprostatectomy, 69% of patients in group 1 were free of BCR, whereas 26% of those in group 2 remained BCR free, suggesting that patients with periprostatic Buparlisib node metastasis appeared to have a lower risk of BCR. However, the difference was not statistically significant (P = .072). The same was true when adjusted for the effect of prostate-specific antigen, surgical margin status, size of LNs, size of metastasis, age, and year of surgery. Conclusion. Patients with periprostatic node metastasis may have a lower risk of BCR compared with those with metastasis to pelvic LN. Future analysis of larger cohorts will help establish the biologic significance of prostate cancer metastasis to periprostatic LN.”
“Naphthopyran polymer conjugates of various rigidities were synthesized by atom transfer radical polymerization (ATRP), and their photochromic properties were tested within a rigid host matrix. Broad tuning of photochromic kinetics was displayed as a result of polymer conjugation because of its ability to alter the local environment of the naphthopyran within the host. End-functionalized conjugates, synthesized from a naphthopyran-functionalized ATRP initiator, allowed systematic tuning of kinetics via modulation of chain length of attached polymer.

The enhancement in the fluorescence intensity was found proportio

The enhancement in the fluorescence intensity was found proportional to the concentration of AMP over the range 2.0 x 10(-4) to 1.2 x 10(-3) AZD1480 in vitro mol dm(-3). The ion pair complex is formed spontaneously between 9-ANCA and CTAB. Since the binding interaction is larger for the adenosine-CTAB pair, the fluorophore 9-ANCA will be released. The quantum yield of free 9-ANCA is higher therefore its fluorescence observed at 417 nm wavelength is enhanced. This mechanism of competitive molecular interaction is further confirmed by conductometric measurements. The method was applied successfully for the determination of AMP from

pharmaceutical sample. The method is more selective, sensitive and relatively free from interferences.”
“Objective: Diastolic dysfunction precedes systolic dysfunction during the development of myocardial ischemia. Detecting diastolic dysfunction during stress test for coronary artery disease (CAD) could improve diagnostic sensitivity of the test. Flow propagation velocity (FPV) derived from color M-mode Doppler has been proposed as a sensitive marker to detect diastolic dysfunction. Methods: The FPVs at baseline find more and at peak dobutamine

infusion were measured using color M-mode Doppler during dobutamine stress echocardiography in 90 patients. The results are compared among the groups divided on the results of coronary angiography. Results: The FPV was similar at baseline among the groups. At peak dobutamine infusion, the FPV increased significantly in the non-CAD group (from 56 +/- 19 cm/s to 66 +/-

25 cm/s), whereas it failed to increase in the groups with CAD. As a result, the peak FPV was significantly lower in the groups with CAD than in the non-CAD group. Receiver operating characteristic analysis showed that the peak FPV and delta FPV had good diagnostic property to detect CAD (the areas under the curves were 0.77 and selleck products 0.73, respectively). Adopting these FPV criteria, sensitivity of DSE was improved. Conclusion: FPV measurement during DSE detects ischemic left ventricular diastolic dysfunction. Adding the assessment of peak FPV to conventional DSE increases the sensitivity and the ability to reliably exclude CAD. (Echocardiography 2011;28:335-341).”
“BACKGROUND AND OBJECTIVES: Because no previous studies have addressed the issue, we describe clinical characteristics and surgical outcome of patients with rhegmatogenous retinal detachment (RRD) in a pediatric population of the Eastern province of Saudi Arabia.\n\nPATIENTS AND METHODS: We conducted a retrospective review of all consecutive cases of pediatric RRD (0-18 years) patients presenting at Dhahran Eye Specialist Hospital, a tertiary care hospital, in the Eastern Province of Saudi Arabia over a period of 3 years.\n\nRESULTS: Twenty patients were included in the study, accounting for 9.4% of all retinal detachment surgery cases performed over a period of 3 years (January 2006 to December 2008).

Leaves of bean had four isoforms of SOD and GDH, two isoforms of

Leaves of bean had four isoforms of SOD and GDH, two isoforms of MDH, five isoforms of G-6-PDH, stems of bean had three isoforms of SOD and MDH, two isoforms of GDH, eight isoforms of G-6-PDH, roots of bean had seven isoforms of AZD5153 price SOD, two isoforms of MDH and five isoforms of G-6-PDH in the non chilling stressed-plants. GDH isoform could not be observed in the root of this plant. Expression of some isoforms

(GDH-4 in the leaf G-6-PDH-1 in the root, G-6-PDH-6 in the stem, G-6-PDH-12 in the leaf) was stopped by chilling stress. While expression of some isoforms was preferentially enhanced or decreased, some isoforms were not changed by chilling stress and PGRs. In addition, expression of new isoforms (G-6-PDH-10, 12, GDH-2) was occurred by chilling stress and PGRs. These results collectively suggest that changes in isoforms of enzymes may be effective on chilling resistance (CR) and PGRs may have a pivotal role for chilling injury in plants.”
“This paper investigates the cluster synchronization problem of a class of general complex dynamical networks under pinning control scheme. The network topology is assumed to be directed

and weakly connected. The pinning controllers are designed according to the nodes property respectively, that is, the inter-act nodes and the intra-act nodes. Some simple control criteria are proposed to guarantee that the nodes synchronize GSK923295 cost with one another in the same cluster, but no synchronization appears AG-881 cell line among the different clusters. Furthermore, an adaptive pinning control approach is developed. Numerical example is also provided to demonstrate the effectiveness of the theoretical analysis. (C) 2012 Elsevier B.V. All rights reserved.”
“IMPORTANCE Geographic atrophy (GA) is the major cause of blind registration in Western communities, although, with few exceptions, it is less common than choroidal neovascular disease. The variation of phenotype implies that age-related macular degeneration (AMD)

does not follow the same course from one case to another and that phenotyping may be important before initiating a therapeutic trial. OBJECTIVE To document photoreceptor and retinal pigment epithelium (RPE) cell loss and other changes at the RPE-choroid interface in donated human eyes in which visual loss was deemed to be due to GA. DESIGN. SETTING. AND PARTICIPANTS Histological study of a consecutive series of eyes donated by individuals previously diagnosed clinically as having GA. Donors were chosen on the basis of available clinical records (from MidAmerica Transplant Services, St Louis, Missouri; the Iowa Lions Eye Bank, Iowa City; and the Utah Lions Eye Bank, Salt Lake City) and selected were those considered to have GA due to AMD. Tissues in the regions of atrophy were examined with light, electron, and autofluorescence microscopy.

The threshold was defined as the point at which the fitted

The threshold was defined as the point at which the fitted

function crossed 50% detection.\n\nResults. Data were well fit by the logistic function in all 4 patients for both RF and non-RF conditions. None of the volunteers tested see more showed a statistically significant difference in detection threshold, reaction time, or in the slope of the psychometric function for stimuli presented inside or outside the RF.\n\nConclusions. Subdural electrodes implanted for extraoperative monitoring do not impair psychophysical performance for a task based on stimuli lying within the RF for recording electrodes. This finding suggests that these electrodes can be used reliably for accurate assessment of regional neurological function.”
“Hepatorenal syndrome (HRS) is a complication of cirrhosis with a poor prognosis without transplantation. The aim of this study is to analyze the influence of extended criteria donors (ECD) on the postoperative outcome of recipients with HRS. The last 498 patients were divided according to pre-transplant type 1 or 2 HRS. Sixty-six (13.25%) recipients fulfilled HRS criteria. Three-month graft survival was

84% with at-listing recipient serum creatinine ranging from 0-0.8 mg/dL; 80% with s-creatinine = 0.9-1.5 mg/dL; 79% with s-creatinine = 1.6-2.5 mg/dL; and 58% with s-creatinine > 2.6 mg/dL (log-rank = 18.039; p = 0.001). Recipients with HRS presented higher levels of pre-transplant creatinine and lower levels of sodium, more episodes of hemodialysis and ascitis, and higher model of end-stage liver disease-scores. Three-month selleck inhibitor graft survival in recipients with HRS relative to ECD-variables showed differences in univariate analysis according to graft steatosis (85% in absent steatosis = 0-10%; 78% in mild steatosis = 10-30%; 76% in moderate steatosis = 30-60%; and 49% when severe steatosis

> 60%; URMC-099 in vivo log-rank = 5.146; p = 0.023). Cox-proportional-hazard-model revealed that graft macrosteatosis per-30%-increments (p = 0.000; HR = 1.303 [1.24-1.33] per-30%-increment) and donors > 65 yr (p = 0.089; HR = 1.622 [1.17-1.94]) were independent predictors of graft loss in recipients with HRS. In conclusion, the use of ECD in recipients with cirrhosis and HRS is a good option. However, grafts from moderate-to-severe steatosis and those from aged donors must be carefully allocated in candidates with HRS.”
“Meat quality and composition characteristics are reported for the longissimus muscle from 10 red deer stags and 10 hinds aged about 20 months. All animals were pasture-finished but the stags and hinds came from different farms. The average carcass weight was 3.4 kg greater for the stag group (55.8 vs 52.4 kg; P = 0.04), but measures of GR as a measure of fatness were similar and intramuscular fat content was significantly greater for the hind group (1.12% vs 0.63%; P<0.0001), as expected.

(c) 2012 Elsevier Ltd All rights reserved “
“During 2004-20

(c) 2012 Elsevier Ltd. All rights reserved.”
“During 2004-2006, two hypomethylating agents (HMAs) were approved for the treatment of myelodysplastic syndromes (MDS) in the United States. We assessed the impact of HMAs on the cost of care and survival of MDS patients, by constructing a cohort of patients who were diagnosed during 2001-2007 (n = 6556, age >= 66.5 years) and comparable non-cancer controls. We assessed MDS patients’ and controls’ Medicare expenditures to

derive MDS-related cost. We evaluated PXD101 research buy the two-year survival of patients as a group and by major subtypes. Taking into account the survival probabilities of MDS, the expected MDS-related 5-year cost was $63,223 (95% confidence interval: $59,868-66,432 in 2009 dollars), higher than the reported comparable cost for any of the 18 most prevalent cancers in the United States. Compared with CH5183284 price MDS patients diagnosed in the earlier period (January 2001-June 2004) who received no HMAs, patients diagnosed later (July 2004-December 2007) who received HMAs had a significantly higher 24-month cost ($97,977 vs. $42,628 in 2009 dollars) and an improved 24-month survival (especially among patients with refractory anemia or refractory anemia with excess blasts). The magnitude of the cost of care underscores

a need for comparative cost-effectiveness studies to reduce the clinical and economic burden of MDS. (C) 2012 Elsevier Ltd. All rights reserved.”
“A novel membrane-less microbial fuel cell (MFC) with down-flow feeding was constructed to generate electricity. Wastewater was fed directly onto the cathode which was horizontally installed in the upper part of the MFC. Oxygen could

be utilized readily from the air. The concentration of dissolved oxygen in the influent wastewater had little effect on the power generation. A saturation-type relationship was observed between the initial COD and the power generation. The influent flow rate could affect greatly hypoxia-inducible factor pathway the power density. Fed by the synthetic glucose wastewater with a COD value of 3500 mg/L at a flow rate of 4.0 mL/min, the developed MFC could produce a maximum power density of 37.4 mW/m(2). Its applicability was further evaluated by the treatment of brewery wastewater. The system could be scaled up readily due to its simple configuration, easy operation and relatively high power density. (C) 2011 Elsevier Ltd. All rights reserved.”
“Objective: Prevalence and clinical relevance of patellofemoral (PF) osteoarthritis (OA) after anterior cruciate ligament (ACL) injury.\n\nMethod: Prospectively we studied 94 out of 100 consecutive patients 15 years after acute ACL injury. ACL reconstructions were only performed late if recurrent “give way” persisted or a secondary meniscal injury suitable for repair occurred. The subjects, mean age 42 years, had knee radiographs including skyline PF view taken, which were graded according to the atlas of the Osteoarthritis Research Society International.