sodium bicarbonate (1:1 randomization).
Materials and Methods: Serum and urinary NGAL were evaluated before and after 8-12, and 24 hours after PCI. Serum cystatin C, serum creatinine, estimated glomerular filtration rate using different formulae were assessed before PCI, and 24 hours after the procedure.
Results: Only 2 patients (2.8%) from the
saline-hydrated group fulfilled the criteria for CI-AKI. In patients hydrated with sodium bicarbonate serum creatinine declined significantly (p<0.01). In patients hydrated with sodium bicarbonate a significant fall in serum NGAL after 8-12 hours was found. In sodium bicarbonate group cystatin C decreased non significantly after 8-12 hours, then returned to the baseline SRT2104 inhibitor values. In patients selleck compound hydrated with physiological saline serum NGAL before PCI and after 24 hours correlated positively with cystatin C and eGFR by CKD-EPI. In patients hydrated with sodium bicarbonate baseline serum NGAL correlated with NGAL baseline cystatin C and eGFR by CKD-EPI,
similarly serum NGAL after 24 hours correlated with cystatin C.
Conclusion: We suggest to rather use sodium bicarbonate in a hydration protocol in patients undergoing PCI. However, the value of NGAL in this setting remains to be elucidated and volume expansion remain the unquestionable prevention methods of CI-AKI.”
“The analytical IPI-145 concentration solutions of the ideal laminate theory-based gas transport model are obtained for inorganic/organic hybrid structures used in gas barrier applications. Nondimensionalized solutions are provided for two cases that can be encountered in real applications: (1) gas diffusion-into and (2) gas transmission-through the barrier structures. The two cases represent (1) gas absorption into flexible organic electronic devices encapsulated by barrier structures and (2) the conventional gas transmission test conditions of barrier structures, respectively. The solutions are utilized to address gas transport behavior in two important practical applications.
(C) 2009 American Institute of Physics. [DOI: 10.1063/1.3116546]“
“Purpose: The most important index of renal function is estimated glomerular filtration rate (eGFR) which can be calculated from creatinine or cystatin C concentration in serum. There is uncertainty, which formula is best suited to assess renal function in morbidly obese patients. The aim of this study was to evaluate eGFR in patients with morbid obesity using formulas: Modification of Diet in Renal Disease (MDRD), Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), Grubb, Le Bricon, Hoek, Larsson, and to compare the obtained results.
Material and Methods: In 40 morbidly obese patients, serum concentration of cystatin C and creatinine were assayed. Values of eGFR were calculated using the above-mentioned formulas.