ORIGINAL ABSTRACT CITATION: “”Comparison of the Clinical Results of Three Posterior Cruciate Ligament Reconstruction Techniques”" (2009;91:2543-9).”
“Swiss albino mice (25 +/- 5 g, either sex) were distributed into 5 groups (n = 12). Group I and II mice served as normal control and EAC control, respectively, Group III, IV and V mice received cisplatin 3.5 mg/kg, i.p., turmeric and mint, 500 mg/kg, orally, respectively, for nine days. Experimental tumor was induced in mice by inoculation of 1×10(6) Ehrlich ascites carcinoma cells AZD6244 (EAC). Change in body weight, survival time, ascites fluid volume and packed
cell volume were noted. At the end of study, WBC, RBC, Hemoglobin content in blood and lipid peroxidation (LPO), superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH) in liver homogenate were estimated. Turmeric and mint treatment in EAC bearing mice showed reduction
in body weight, tumor volume, packed cell volume and percentage increase in life span, increased RBC and Hb, reduced WBC count and normalized antioxidant parameters. Aqueous HM781-36B extract of mint and turmeric exhibited significant (p < 0.001) anticancer activity in mice. Mint showed superior anticancer activity than turmeric.”
“BACKGROUND: The treatment of complex diaphyseal malunions is challenging, requiring extensive preoperative planning and precise operative technique. We have developed a simpler method to treat some of these deformities.
METHODS: Ten patients with complex diaphyseal malunions (including four femoral and six tibial malunions) underwent a clamshell osteotomy. The indications for surgery included pain at adjacent joints and deformity. After surgical exposure, the malunited segment was transected perpendicular to the normal diaphysis proximally and distally. The transected
segment was again osteotomized along its long axis and was wedged open, similar to opening a clamshell. The proximal and distal segments of the CCI-779 PI3K/Akt/mTOR inhibitor diaphysis were then aligned with use of an intramedullary rod as an anatomic axis template and with use of the contralateral extremity as a length and rotation template. The patients were assessed clinically and radiographically at a mean of thirty-one months (range, six to fifty-two months) after the osteotomy.
RESULTS: Complete angular correction was achieved in each case; the amount of correction ranged from 20 to 20 in the coronal plane, from 0 to 32 in the sagittal plane, and from 0 to 25 in the axial plane (rotation). Correction of length ranged from 0 to 5 cm, and limb length was restored to within 2 cm in all patients. All osteotomy sites were healed clinically by six months. While no deep infections occurred, superficial wound dehiscence occurred in two patients along the approach for the longitudinal portion of the osteotomy, emphasizing the importance of careful soft-tissue handling and patient selection.