The exchange nonlinear contribution κ′ex is important for R < 300 nm. However, the authors of [19–21] did not consider it at all. Note that N(0.089, 300 nm, 0) ≈ 0.5 Volasertib ic50 recently measured [29] is two times larger than 0.25. The authors of [19] suggested

to use an additional term ~u 6 in the magnetic energy fitting the nonlinear frequency due to accounting a u 4-contribution (N = 0.26) that is too small based on [14], while the nonlinear coefficient N(β, R) calculated by Equation 5 for the parameters of Py dots (L = 4.8 nm, R = 275 nm) [19] is equal to 0.38. Moreover, the authors of [19] did not account that, for a high value of the vortex amplitude u = 0.6 to 0.7, the contribution of nonlinear gyrovector G(u) ∝ c 2 u 2 to the vortex frequency is more important than the u 6-magnetic energy term. The gyrovector G(u) decreases essentially for such a large u resulting in the nonlinear frequency increase. The TVA calculations based on Equation 5 lead to the small nonlinear Oe energy contribution κ′Oe, whereas Dussaux et al. [19] stated that κ′Oe is more important than the magnetostatic nonlinear contribution. Conclusions We demonstrated that the generalized Thiele equation of motion (1) with the nonlinear coefficients (2) considered beyond the rigid vortex approximation

Selumetinib solubility dmso can be successfully used for quantitative description of the nonlinear vortex STNO dynamics excited by spin-polarized current in a AP24534 circular nanodot. We calculated the nonlinear parameters governing the vortex core large-amplitude oscillations and showed that the analytical two-vortex model can predict the parameters, which are in good agreement with the ones simulated numerically. The Thiele approach and the energy dissipation approach [12, 19] are equivalent because they are grounded on the same LLG equation of magnetization motion. The limits of applicability of the nonlinear oscillator approach ID-8 developed for saturated nanodots [13] to vortex STNO dynamics are established. The calculated and simulated dependences

of the vortex core orbit radius u(t) and phase Φ(t) can be used as a starting point to consider the transient dynamics of synchronization of two coupled vortex ST nano-oscillators in laterally located circular nanopillars [30] or square nanodots with circular nanocontacts [31] calculated recently. Acknowledgements This work was supported in part by the Spanish MINECO grant FIS2010-20979-C02-01. KYG acknowledges support by IKERBASQUE (the Basque Foundation for Science). References 1. Rowlands GE, Krivorotov IN: Magnetization dynamics in a dual free-layer spin torque nano-oscillator. Phys Rev B 2012,86(094425):7. 2. Pribiag VS, Krivorotov IN, Fuchs GD, Braganca PM, Ozatay O, Sankey JC, Ralph DC, Buhrman RA: Magnetic vortex oscillator driven by d.c. spin-polarized current. Nat Phys 2007, 3:498–503. 10.1038/nphys619CrossRef 3.