Isotransplantation was performed by end-to-side anastomosis of the blood vessels and end-to-end anastomosis of the ureters. Irrigating the donor kidney before dissection provided a clear visual field, reduced the operation time (37.50 ± 6.84 versus 68.30 ± 11.53 minutes, p < 0.001), facilitated the dissection of vessels, and reduced the risk of vasospasm (5 out of 19 versus 0
out of 18, p < 0.05). This study has demonstrated the proposed technique is fast and safe, and may be useful in research of renal transplantation in the rat model. © 2010 Wiley-Liss, Inc. Microsurgery 30:569–573, 2010. "
“Department of Plastic and Hand Surgery, University of Freiburg Medical Centre, Freiburg, Germany Chronic lymphedema is a debilitating complication of cancer diagnosis Epacadostat and therapy and poses many challenges for health care professionals. It remains a poorly understood condition that has the potential to occur after any intervention affecting lymph node drainage mechanism. Microsurgical lymph vessel transplantation is increasingly recognized as a promising method for bypassing the obstructed lymph pathways and promoting long-term reduction of edema in the affected limb. A detailed review of 14 patients with postoperative lymphedema Z-VAD-FMK cell line treated with autologous lymph vessel transplantation
between October 2005 and November 2009 was performed. In this report, the authors gave an account of their experience in utilizing this operative method to alleviate secondary lymphedema including upper limb, lower limb, genital, and facial edemas. Lymph vessel transplantation enhanced lymphatic drainage in patients with secondary lymphedema. In the upper and lower extremities, three patients had completed symptomatic recovery and another nine patients achieved reasonable reduction of lymphedema, four of these needed no further lymph drainage or compression garments and the remaining maintained their improvement with
further decongestive therapy with or without compression garments. The patients with facial and genital edemas also experienced significant symptomatic improvement. Thiamine-diphosphate kinase The authors were able to establish long-term patency of the lymph vessel anastomosis by magnetic resonance lymphangiography. © 2011 Wiley Periodicals, Inc. Microsurgery, 2012. “
“Several types of nerve conduits have been used for peripheral nerve gap bridging. This study investigated the in vivo engineering of a biological nerve conduit and its suitability for nerve gap bridging. A 19-mm long polyvinyl chloride (PVC) tube was implanted parallely to the sciatic nerve. After implantation, a connective tissue cover developed around the PVC-tube, the so-called biogenic conduit. Histological cross-sections were performed after 1, 2, 3, and 4 weeks.